BDBM50189864 CHEMBL3827601

SMILES: CC(Oc1ccc2[nH]nc(-c3nc4cc(F)ccc4[nH]3)c2c1)c1c(Cl)cncc1Cl

InChI Key: InChIKey=BCBKLTORPXXDMJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50189864 (CHEMBL3827601) Show SMILES CC(Oc1ccc2[nH]nc(-c3nc4cc(F)ccc4[nH]3)c2c1)c1c(Cl)cncc1Cl Show InChI InChI=1S/C21H14Cl2FN5O/c1-10(19-14(22)8-25-9-15(19)23)30-12-3-5-16-13(7-12)20(29-28-16)21-26-17-4-2-11(24)6-18(17)27-21/h2-10H,1H3,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science& Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 59: 6690-708 (2016) BindingDB Entry DOI: 10.7270/Q2474CT3
					More data for this Ligand-Target Pair