BDBM50189870 CHEMBL3827818
SMILES: CC(Oc1ccc2[nH]nc(-c3nc4cc(ccc4[nH]3)N3CCOCC3)c2c1)c1c(Cl)cncc1Cl
InChI Key: InChIKey=GPPKLMYVHZCXOC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM50189870 (CHEMBL3827818) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science& Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA | J Med Chem 59: 6690-708 (2016) BindingDB Entry DOI: 10.7270/Q2474CT3 | |||||||||||
More data for this Ligand-Target Pair |