null

SMILES: Nc1ccc(cc1NC(=O)C1CCc2ccccc2O1)-c1ccc(F)cc1

InChI Key: InChIKey=ABPFJJGEOBFFPG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189907   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50189907 (CHEMBL3828015) Show SMILES Nc1ccc(cc1NC(=O)C1CCc2ccccc2O1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H19FN2O2/c23-17-9-5-14(6-10-17)16-7-11-18(24)19(13-16)25-22(26)21-12-8-15-3-1-2-4-20(15)27-21/h1-7,9-11,13,21H,8,12,24H2,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Broad Institute of MIT and Harvard Curated by ChEMBL					Assay Description Inhibition full length human recombinant HDAC3 expressed in baculovirus using carboxyfluorescein (FAM)-labeled acetylated/ trifluoroacetylated peptid...				Bioorg Med Chem 24: 4008-4015 (2016) BindingDB Entry DOI: 10.7270/Q23B6220
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50189907 (CHEMBL3828015) Show SMILES Nc1ccc(cc1NC(=O)C1CCc2ccccc2O1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H19FN2O2/c23-17-9-5-14(6-10-17)16-7-11-18(24)19(13-16)25-22(26)21-12-8-15-3-1-2-4-20(15)27-21/h1-7,9-11,13,21H,8,12,24H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Broad Institute of MIT and Harvard Curated by ChEMBL					Assay Description Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...				Bioorg Med Chem 24: 4008-4015 (2016) BindingDB Entry DOI: 10.7270/Q23B6220
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50189907 (CHEMBL3828015) Show SMILES Nc1ccc(cc1NC(=O)C1CCc2ccccc2O1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H19FN2O2/c23-17-9-5-14(6-10-17)16-7-11-18(24)19(13-16)25-22(26)21-12-8-15-3-1-2-4-20(15)27-21/h1-7,9-11,13,21H,8,12,24H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Broad Institute of MIT and Harvard Curated by ChEMBL					Assay Description Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...				Bioorg Med Chem 24: 4008-4015 (2016) BindingDB Entry DOI: 10.7270/Q23B6220
					More data for this Ligand-Target Pair