BDBM50190015 (4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophenyl)thiophen-2-yl)(hydroxy)methyl)-1-methylpyrrolidin-2-one::CHEMBL215578

SMILES: CN1[C@@H]([C@H](O)c2ccc(s2)S(=O)(=O)c2ccccc2)[C@H](CC1=O)c1ccccc1F

InChI Key: InChIKey=YLJLDGJNPAMFFR-NPFVIJTESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol 17-beta-dehydrogenase 2 (Homo sapiens (Human))	BDBM50190015 ((4R,5R)-4-(2-fluorophenyl)-5-((S)-(5-(4-fluorophen...) Show SMILES CN1[C@@H]([C@H](O)c2ccc(s2)S(=O)(=O)c2ccccc2)[C@H](CC1=O)c1ccccc1F Show InChI InChI=1S/C22H20FNO4S2/c1-24-19(25)13-16(15-9-5-6-10-17(15)23)21(24)22(26)18-11-12-20(29-18)30(27,28)14-7-3-2-4-8-14/h2-12,16,21-22,26H,13H2,1H3/t16-,21-,22-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant 17beta-HSD2				Bioorg Med Chem Lett 16: 4965-8 (2006) Article DOI: 10.1016/j.bmcl.2006.06.041 BindingDB Entry DOI: 10.7270/Q2GB24V1
					More data for this Ligand-Target Pair