BDBM50190045 8-chloro-11-[4-(2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-piperazin-1-yl]-5H-dibenzo[b,e][1,4]diazepine::CHEMBL213577

SMILES: Clc1ccc2Nc3ccccc3C(=Nc2c1)N1CCN(Cc2ccc3OCCOc3c2)CC1

InChI Key: InChIKey=YNYGWSSJOCRJGL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50190045 (8-chloro-11-[4-(2,3-dihydro-benzo[1,4]dioxin-6-ylm...) Show SMILES Clc1ccc2Nc3ccccc3C(=Nc2c1)N1CCN(Cc2ccc3OCCOc3c2)CC1 |c:13| Show InChI InChI=1S/C26H25ClN4O2/c27-19-6-7-22-23(16-19)29-26(20-3-1-2-4-21(20)28-22)31-11-9-30(10-12-31)17-18-5-8-24-25(15-18)33-14-13-32-24/h1-8,15-16,28H,9-14,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4548-53 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.06.034 BindingDB Entry DOI: 10.7270/Q2MG7P4R
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50190045 (8-chloro-11-[4-(2,3-dihydro-benzo[1,4]dioxin-6-ylm...) Show SMILES Clc1ccc2Nc3ccccc3C(=Nc2c1)N1CCN(Cc2ccc3OCCOc3c2)CC1 |c:13| Show InChI InChI=1S/C26H25ClN4O2/c27-19-6-7-22-23(16-19)29-26(20-3-1-2-4-21(20)28-22)31-11-9-30(10-12-31)17-18-5-8-24-25(15-18)33-14-13-32-24/h1-8,15-16,28H,9-14,17H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	583	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from dopamine D1 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4548-53 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.06.034 BindingDB Entry DOI: 10.7270/Q2MG7P4R
					More data for this Ligand-Target Pair