BDBM50190056 CHEMBL213239::N-[2-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-3-methoxy-benzamide

SMILES: COc1cccc(c1)C(=O)NN1c2ccccc2N=C(N2CCN(C)CC2)c2cc(Cl)ccc12

InChI Key: InChIKey=CHIWZHUPHKIHAQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50190056 (CHEMBL213239 | N-[2-chloro-11-(4-methyl-piperazin-...) Show SMILES COc1cccc(c1)C(=O)NN1c2ccccc2N=C(N2CCN(C)CC2)c2cc(Cl)ccc12 |t:20| Show InChI InChI=1S/C26H26ClN5O2/c1-30-12-14-31(15-13-30)25-21-17-19(27)10-11-23(21)32(24-9-4-3-8-22(24)28-25)29-26(33)18-6-5-7-20(16-18)34-2/h3-11,16-17H,12-15H2,1-2H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from dopamine D1 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4548-53 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.06.034 BindingDB Entry DOI: 10.7270/Q2MG7P4R
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50190056 (CHEMBL213239 | N-[2-chloro-11-(4-methyl-piperazin-...) Show SMILES COc1cccc(c1)C(=O)NN1c2ccccc2N=C(N2CCN(C)CC2)c2cc(Cl)ccc12 |t:20| Show InChI InChI=1S/C26H26ClN5O2/c1-30-12-14-31(15-13-30)25-21-17-19(27)10-11-23(21)32(24-9-4-3-8-22(24)28-25)29-26(33)18-6-5-7-20(16-18)34-2/h3-11,16-17H,12-15H2,1-2H3,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4548-53 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.06.034 BindingDB Entry DOI: 10.7270/Q2MG7P4R
					More data for this Ligand-Target Pair