BDBM50190073 CHEMBL384269::N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2,3-difluoro-benzamide

SMILES: CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc(F)c2F)c2ccccc12

InChI Key: InChIKey=YPMXEBRQAPTSOE-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50190073 (CHEMBL384269 | N-[8-chloro-11-(4-methyl-piperazin-...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc(F)c2F)c2ccccc12 |t:8| Show InChI InChI=1S/C25H22ClF2N5O/c1-31-11-13-32(14-12-31)24-17-5-2-3-8-21(17)33(22-10-9-16(26)15-20(22)29-24)30-25(34)18-6-4-7-19(27)23(18)28/h2-10,15H,11-14H2,1H3,(H,30,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from dopamine D1 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4548-53 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.06.034 BindingDB Entry DOI: 10.7270/Q2MG7P4R
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50190073 (CHEMBL384269 | N-[8-chloro-11-(4-methyl-piperazin-...) Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc(F)c2F)c2ccccc12 |t:8| Show InChI InChI=1S/C25H22ClF2N5O/c1-31-11-13-32(14-12-31)24-17-5-2-3-8-21(17)33(22-10-9-16(26)15-20(22)29-24)30-25(34)18-6-4-7-19(27)23(18)28/h2-10,15H,11-14H2,1H3,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	533	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4548-53 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.06.034 BindingDB Entry DOI: 10.7270/Q2MG7P4R
					More data for this Ligand-Target Pair