BDBM50190094 CHEMBL212807::N-[2,8-dichloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2,6-dimethoxy-benzamide

SMILES: COc1cccc(OC)c1C(=O)NN1c2ccc(Cl)cc2N=C(N2CCN(C)CC2)c2cc(Cl)ccc12

InChI Key: InChIKey=QGFMLINRMXISAI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50190094 (CHEMBL212807 | N-[2,8-dichloro-11-(4-methyl-pipera...) Show SMILES COc1cccc(OC)c1C(=O)NN1c2ccc(Cl)cc2N=C(N2CCN(C)CC2)c2cc(Cl)ccc12 |t:23| Show InChI InChI=1S/C27H27Cl2N5O3/c1-32-11-13-33(14-12-32)26-19-15-17(28)7-9-21(19)34(22-10-8-18(29)16-20(22)30-26)31-27(35)25-23(36-2)5-4-6-24(25)37-3/h4-10,15-16H,11-14H2,1-3H3,(H,31,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from dopamine D1 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4548-53 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.06.034 BindingDB Entry DOI: 10.7270/Q2MG7P4R
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50190094 (CHEMBL212807 | N-[2,8-dichloro-11-(4-methyl-pipera...) Show SMILES COc1cccc(OC)c1C(=O)NN1c2ccc(Cl)cc2N=C(N2CCN(C)CC2)c2cc(Cl)ccc12 |t:23| Show InChI InChI=1S/C27H27Cl2N5O3/c1-32-11-13-33(14-12-32)26-19-15-17(28)7-9-21(19)34(22-10-8-18(29)16-20(22)30-26)31-27(35)25-23(36-2)5-4-6-24(25)37-3/h4-10,15-16H,11-14H2,1-3H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute K15 2545 Curated by ChEMBL					Assay Description Displacement of [3H]methylspiperone from dopamine D2 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 4548-53 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.06.034 BindingDB Entry DOI: 10.7270/Q2MG7P4R
					More data for this Ligand-Target Pair