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BDBM50190111 CHEMBL327844

SMILES: NC(CCc1ccccc1)P(O)(=O)CC(Cc1ccccc1)C(O)=O

InChI Key: InChIKey=QELOIXSGJMIHBZ-UHFFFAOYSA-N

Data: 5 KI

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50190111
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
leucine aminopeptidase (Plasmodium falciparum 3D7)	BDBM50190111 (CHEMBL327844) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum LAP				Bioorg Med Chem Lett 29: 1031-1042 (2019) Article DOI: 10.1016/j.bmcl.2019.02.034
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytosol aminopeptidase (Sus scrofa)	BDBM50190111 (CHEMBL327844) Show SMILES Show InChI	MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of porcine LAP				Bioorg Med Chem Lett 29: 1031-1042 (2019) Article DOI: 10.1016/j.bmcl.2019.02.034
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50190111 (CHEMBL327844) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of porcine APN				Bioorg Med Chem Lett 29: 1031-1042 (2019) Article DOI: 10.1016/j.bmcl.2019.02.034
					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50190111 (CHEMBL327844) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase (Homo sapiens (Human))	BDBM50190111 (CHEMBL327844) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of human ERAP1 preincubated for 30 to 60 mins followed by addition of Leu-AMC as substrate measured for 15 mins by spectrofluorimetric met...				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair