Found 7 hits for monomerid = 50190193 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50190193
(CHEMBL213834 | naphthalene-1-carboxylic acid [8-ch...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12 |t:8| Show InChI InChI=1S/C29H26ClN5O/c1-33-15-17-34(18-16-33)28-24-10-4-5-12-26(24)35(27-14-13-21(30)19-25(27)31-28)32-29(36)23-11-6-8-20-7-2-3-9-22(20)23/h2-14,19H,15-18H2,1H3,(H,32,36) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Binding affinity at 5HT2A receptor |
Bioorg Med Chem Lett 16: 4543-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.022 BindingDB Entry DOI: 10.7270/Q2GT5MSW |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(Homo sapiens (Human)) | BDBM50190193
(CHEMBL213834 | naphthalene-1-carboxylic acid [8-ch...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12 |t:8| Show InChI InChI=1S/C29H26ClN5O/c1-33-15-17-34(18-16-33)28-24-10-4-5-12-26(24)35(27-14-13-21(30)19-25(27)31-28)32-29(36)23-11-6-8-20-7-2-3-9-22(20)23/h2-14,19H,15-18H2,1H3,(H,32,36) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]SCH 23390 from human dopamine D1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 4543-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.022 BindingDB Entry DOI: 10.7270/Q2GT5MSW |
More data for this Ligand-Target Pair | |
D(1B) dopamine receptor
(Homo sapiens (Human)) | BDBM50190193
(CHEMBL213834 | naphthalene-1-carboxylic acid [8-ch...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12 |t:8| Show InChI InChI=1S/C29H26ClN5O/c1-33-15-17-34(18-16-33)28-24-10-4-5-12-26(24)35(27-14-13-21(30)19-25(27)31-28)32-29(36)23-11-6-8-20-7-2-3-9-22(20)23/h2-14,19H,15-18H2,1H3,(H,32,36) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Binding affinity at dopamine D5 receptor |
Bioorg Med Chem Lett 16: 4543-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.022 BindingDB Entry DOI: 10.7270/Q2GT5MSW |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50190193
(CHEMBL213834 | naphthalene-1-carboxylic acid [8-ch...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12 |t:8| Show InChI InChI=1S/C29H26ClN5O/c1-33-15-17-34(18-16-33)28-24-10-4-5-12-26(24)35(27-14-13-21(30)19-25(27)31-28)32-29(36)23-11-6-8-20-7-2-3-9-22(20)23/h2-14,19H,15-18H2,1H3,(H,32,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 458 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Displacement of [3H]methylspiperone from human dopamine D2 receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 4543-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.022 BindingDB Entry DOI: 10.7270/Q2GT5MSW |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50190193
(CHEMBL213834 | naphthalene-1-carboxylic acid [8-ch...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12 |t:8| Show InChI InChI=1S/C29H26ClN5O/c1-33-15-17-34(18-16-33)28-24-10-4-5-12-26(24)35(27-14-13-21(30)19-25(27)31-28)32-29(36)23-11-6-8-20-7-2-3-9-22(20)23/h2-14,19H,15-18H2,1H3,(H,32,36) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 458 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Binding affinity at dopamine D2 receptor |
Bioorg Med Chem Lett 16: 4543-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.022 BindingDB Entry DOI: 10.7270/Q2GT5MSW |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM50190193
(CHEMBL213834 | naphthalene-1-carboxylic acid [8-ch...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12 |t:8| Show InChI InChI=1S/C29H26ClN5O/c1-33-15-17-34(18-16-33)28-24-10-4-5-12-26(24)35(27-14-13-21(30)19-25(27)31-28)32-29(36)23-11-6-8-20-7-2-3-9-22(20)23/h2-14,19H,15-18H2,1H3,(H,32,36) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 882 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Binding affinity at adrenergic alpha2A receptor |
Bioorg Med Chem Lett 16: 4543-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.022 BindingDB Entry DOI: 10.7270/Q2GT5MSW |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50190193
(CHEMBL213834 | naphthalene-1-carboxylic acid [8-ch...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2N(NC(=O)c2cccc3ccccc23)c2ccccc12 |t:8| Show InChI InChI=1S/C29H26ClN5O/c1-33-15-17-34(18-16-33)28-24-10-4-5-12-26(24)35(27-14-13-21(30)19-25(27)31-28)32-29(36)23-11-6-8-20-7-2-3-9-22(20)23/h2-14,19H,15-18H2,1H3,(H,32,36) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 977 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Binding affinity at dopamine D4 receptor |
Bioorg Med Chem Lett 16: 4543-7 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.022 BindingDB Entry DOI: 10.7270/Q2GT5MSW |
More data for this Ligand-Target Pair | |