Found 4 hits for monomerid = 50190255 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50190255
(2-(aminosulfonyl)-5-chloro-4-methylphenyl N-(4-nit...)Show SMILES Cc1cc(c(SC(=NNc2ccc(cc2)[N+]([O-])=O)c2ccccc2)cc1Cl)S(N)(=O)=O |w:7.7| Show InChI InChI=1S/C20H17ClN4O4S2/c1-13-11-19(31(22,28)29)18(12-17(13)21)30-20(14-5-3-2-4-6-14)24-23-15-7-9-16(10-8-15)25(26)27/h2-12,23H,1H3,(H2,22,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk
Curated by ChEMBL
| Assay Description Inhibition of human cloned CA12 catalytic domain by CO2 hydration assay |
Bioorg Med Chem Lett 16: 4846-51 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.064 BindingDB Entry DOI: 10.7270/Q2794493 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50190255
(2-(aminosulfonyl)-5-chloro-4-methylphenyl N-(4-nit...)Show SMILES Cc1cc(c(SC(=NNc2ccc(cc2)[N+]([O-])=O)c2ccccc2)cc1Cl)S(N)(=O)=O |w:7.7| Show InChI InChI=1S/C20H17ClN4O4S2/c1-13-11-19(31(22,28)29)18(12-17(13)21)30-20(14-5-3-2-4-6-14)24-23-15-7-9-16(10-8-15)25(26)27/h2-12,23H,1H3,(H2,22,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk
Curated by ChEMBL
| Assay Description Inhibition of human cloned CA2 by CO2 hydration assay |
Bioorg Med Chem Lett 16: 4846-51 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.064 BindingDB Entry DOI: 10.7270/Q2794493 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50190255
(2-(aminosulfonyl)-5-chloro-4-methylphenyl N-(4-nit...)Show SMILES Cc1cc(c(SC(=NNc2ccc(cc2)[N+]([O-])=O)c2ccccc2)cc1Cl)S(N)(=O)=O |w:7.7| Show InChI InChI=1S/C20H17ClN4O4S2/c1-13-11-19(31(22,28)29)18(12-17(13)21)30-20(14-5-3-2-4-6-14)24-23-15-7-9-16(10-8-15)25(26)27/h2-12,23H,1H3,(H2,22,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk
Curated by ChEMBL
| Assay Description Inhibition of human cloned CA9 catalytic domain by CO2 hydration assay |
Bioorg Med Chem Lett 16: 4846-51 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.064 BindingDB Entry DOI: 10.7270/Q2794493 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50190255
(2-(aminosulfonyl)-5-chloro-4-methylphenyl N-(4-nit...)Show SMILES Cc1cc(c(SC(=NNc2ccc(cc2)[N+]([O-])=O)c2ccccc2)cc1Cl)S(N)(=O)=O |w:7.7| Show InChI InChI=1S/C20H17ClN4O4S2/c1-13-11-19(31(22,28)29)18(12-17(13)21)30-20(14-5-3-2-4-6-14)24-23-15-7-9-16(10-8-15)25(26)27/h2-12,23H,1H3,(H2,22,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.79E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Gdansk
Curated by ChEMBL
| Assay Description Inhibition of human cloned CA1 by CO2 hydration assay |
Bioorg Med Chem Lett 16: 4846-51 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.064 BindingDB Entry DOI: 10.7270/Q2794493 |
More data for this Ligand-Target Pair | |