BDBM50190563 1-(4-tert-butyldiphenylsilyloxyhexyl)uracil::CHEMBL211847

SMILES: CC(C)(C)[Si](OCCCCCCn1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=OJOUHIKBDMPHTA-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
dUTP pyrophosphatase (Plasmodium falciparum)	BDBM50190563 (1-(4-tert-butyldiphenylsilyloxyhexyl)uracil | CHEM...) Show SMILES CC(C)(C)[Si](OCCCCCCn1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H34N2O3Si/c1-26(2,3)32(22-14-8-6-9-15-22,23-16-10-7-11-17-23)31-21-13-5-4-12-19-28-20-18-24(29)27-25(28)30/h6-11,14-18,20H,4-5,12-13,19,21H2,1-3H3,(H,27,29,30)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum dUTPase				J Med Chem 49: 4183-95 (2006) Article DOI: 10.1021/jm060126s BindingDB Entry DOI: 10.7270/Q22J6BF0
					More data for this Ligand-Target Pair
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (Homo sapiens (Human))	BDBM50190563 (1-(4-tert-butyldiphenylsilyloxyhexyl)uracil | CHEM...) Show SMILES CC(C)(C)[Si](OCCCCCCn1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H34N2O3Si/c1-26(2,3)32(22-14-8-6-9-15-22,23-16-10-7-11-17-23)31-21-13-5-4-12-19-28-20-18-24(29)27-25(28)30/h6-11,14-18,20H,4-5,12-13,19,21H2,1-3H3,(H,27,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of human recombinant dUTPase				J Med Chem 49: 4183-95 (2006) Article DOI: 10.1021/jm060126s BindingDB Entry DOI: 10.7270/Q22J6BF0
					More data for this Ligand-Target Pair