BDBM50190750 2-((1-((4-benzylpyridin-2-yl)carbamoyl)cyclopentyl)methyl)pentanoic acid::CHEMBL212771

SMILES: CCCC(CC1(CCCC1)C(=O)Nc1cc(Cc2ccccc2)ccn1)C(O)=O

InChI Key: InChIKey=TZGRGYIVZRTXNF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50190750 (2-((1-((4-benzylpyridin-2-yl)carbamoyl)cyclopentyl...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1cc(Cc2ccccc2)ccn1)C(O)=O Show InChI InChI=1S/C24H30N2O3/c1-2-8-20(22(27)28)17-24(12-6-7-13-24)23(29)26-21-16-19(11-14-25-21)15-18-9-4-3-5-10-18/h3-5,9-11,14,16,20H,2,6-8,12-13,15,17H2,1H3,(H,27,28)(H,25,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50190750 (2-((1-((4-benzylpyridin-2-yl)carbamoyl)cyclopentyl...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1cc(Cc2ccccc2)ccn1)C(O)=O Show InChI InChI=1S/C24H30N2O3/c1-2-8-20(22(27)28)17-24(12-6-7-13-24)23(29)26-21-16-19(11-14-25-21)15-18-9-4-3-5-10-18/h3-5,9-11,14,16,20H,2,6-8,12-13,15,17H2,1H3,(H,27,28)(H,25,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog ACE				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair