BDBM50190753 2-((1-((5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl)cyclopentyl)methyl)pentanoic acid::CHEMBL379935

SMILES: CCCC(CC1(CCCC1)C(=O)Nc1nnc(Cc2ccccc2)s1)C(O)=O

InChI Key: InChIKey=WTCGLJIGRQNVRC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM50190753 (2-((1-((5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl)c...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(Cc2ccccc2)s1)C(O)=O Show InChI InChI=1S/C21H27N3O3S/c1-2-8-16(18(25)26)14-21(11-6-7-12-21)19(27)22-20-24-23-17(28-20)13-15-9-4-3-5-10-15/h3-5,9-10,16H,2,6-8,11-14H2,1H3,(H,25,26)(H,22,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog ACE				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50190753 (2-((1-((5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl)c...) Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(Cc2ccccc2)s1)C(O)=O Show InChI InChI=1S/C21H27N3O3S/c1-2-8-16(18(25)26)14-21(11-6-7-12-21)19(27)22-20-24-23-17(28-20)13-15-9-4-3-5-10-15/h3-5,9-10,16H,2,6-8,11-14H2,1H3,(H,25,26)(H,22,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair