BDBM50190764 2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cyclopentyl)methyl)hexanoic acid::CHEMBL212220

SMILES: CCCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O

InChI Key: InChIKey=OELJYWODVDGDGG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50190764 (2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cy...) Show SMILES CCCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C17H27N3O3S/c1-3-5-8-12(14(21)22)11-17(9-6-7-10-17)15(23)18-16-20-19-13(4-2)24-16/h12H,3-11H2,1-2H3,(H,21,22)(H,18,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog NEP				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50190764 (2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cy...) Show SMILES CCCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O Show InChI InChI=1S/C17H27N3O3S/c1-3-5-8-12(14(21)22)11-17(9-6-7-10-17)15(23)18-16-20-19-13(4-2)24-16/h12H,3-11H2,1-2H3,(H,21,22)(H,18,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of dog ACE				J Med Chem 49: 4409-24 (2006) Article DOI: 10.1021/jm060133g BindingDB Entry DOI: 10.7270/Q2930SS8
					More data for this Ligand-Target Pair