BDBM50190851 2-(6-(3-cyanophenyl)-1-(1-(tetrahydrothiophen-3-yl)piperidin-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-(3,5-dichlorophenyl)acetamide::CHEMBL379002

SMILES: Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C2C2CCN(CC2)C2CCSC2)-c2cccc(c2)C#N)c1

InChI Key: InChIKey=BWOQYUBQTJIHJV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190851   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50190851 (2-(6-(3-cyanophenyl)-1-(1-(tetrahydrothiophen-3-yl...) Show SMILES Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C2C2CCN(CC2)C2CCSC2)-c2cccc(c2)C#N)c1 Show InChI InChI=1S/C33H34Cl2N4OS/c34-27-16-28(35)18-29(17-27)37-32(40)20-39-12-8-26-15-25(24-3-1-2-22(14-24)19-36)4-5-31(26)33(39)23-6-10-38(11-7-23)30-9-13-41-21-30/h1-5,14-18,23,30,33H,6-13,20-21H2,(H,37,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 16: 4917-21 (2006) Article DOI: 10.1016/j.bmcl.2006.06.055 BindingDB Entry DOI: 10.7270/Q2WW7H83
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