BDBM50190883 2-(6-(3-cyanophenyl)-1-(1-cyclohexylpiperidin-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-(3,5-dichlorophenyl)acetamide::CHEMBL215259

SMILES: Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C2C2CCN(CC2)C2CCCCC2)-c2cccc(c2)C#N)c1

InChI Key: InChIKey=XNQJWPUOMWMKRZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50190883 (2-(6-(3-cyanophenyl)-1-(1-cyclohexylpiperidin-4-yl...) Show SMILES Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C2C2CCN(CC2)C2CCCCC2)-c2cccc(c2)C#N)c1 Show InChI InChI=1S/C35H38Cl2N4O/c36-29-19-30(37)21-31(20-29)39-34(42)23-41-16-13-28-18-27(26-6-4-5-24(17-26)22-38)9-10-33(28)35(41)25-11-14-40(15-12-25)32-7-2-1-3-8-32/h4-6,9-10,17-21,25,32,35H,1-3,7-8,11-16,23H2,(H,39,42)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 16: 4917-21 (2006) Article DOI: 10.1016/j.bmcl.2006.06.055 BindingDB Entry DOI: 10.7270/Q2WW7H83
					More data for this Ligand-Target Pair