BDBM50190886 2-[6-(3-cyano-phenyl)-1'-cyclobutyl-3,4-dihydro-spiro[isoquinoline-1,4'-piperidin]-2-yl]-N-(3,5-dichloro-phenyl)-acetamide::CHEMBL217581

SMILES: Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C22CCN(CC2)C2CCC2)-c2cccc(c2)C#N)c1

InChI Key: InChIKey=FZTBMMNDYRLJID-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50190886 (2-[6-(3-cyano-phenyl)-1'-cyclobutyl-3,4-dihydro-sp...) Show SMILES Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C22CCN(CC2)C2CCC2)-c2cccc(c2)C#N)c1 Show InChI InChI=1S/C32H32Cl2N4O/c33-26-17-27(34)19-28(18-26)36-31(39)21-38-12-9-25-16-24(23-4-1-3-22(15-23)20-35)7-8-30(25)32(38)10-13-37(14-11-32)29-5-2-6-29/h1,3-4,7-8,15-19,29H,2,5-6,9-14,21H2,(H,36,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 16: 4917-21 (2006) Article DOI: 10.1016/j.bmcl.2006.06.055 BindingDB Entry DOI: 10.7270/Q2WW7H83
					More data for this Ligand-Target Pair