BDBM50190887 2-[6-(3-cyano-phenyl)-1'-cyclopentyl-3,4-dihydro-spiro[isoquinoline-1,4'-piperidin]-2-yl]-N-(3,5-dichloro-phenyl)-acetamide::CHEMBL211978

SMILES: Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C22CCN(CC2)C2CCCC2)-c2cccc(c2)C#N)c1

InChI Key: InChIKey=IFVDAKOERJNKCP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50190887 (2-[6-(3-cyano-phenyl)-1'-cyclopentyl-3,4-dihydro-s...) Show SMILES Clc1cc(Cl)cc(NC(=O)CN2CCc3cc(ccc3C22CCN(CC2)C2CCCC2)-c2cccc(c2)C#N)c1 Show InChI InChI=1S/C33H34Cl2N4O/c34-27-18-28(35)20-29(19-27)37-32(40)22-39-13-10-26-17-25(24-5-3-4-23(16-24)21-36)8-9-31(26)33(39)11-14-38(15-12-33)30-6-1-2-7-30/h3-5,8-9,16-20,30H,1-2,6-7,10-15,22H2,(H,37,40)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 16: 4917-21 (2006) Article DOI: 10.1016/j.bmcl.2006.06.055 BindingDB Entry DOI: 10.7270/Q2WW7H83
					More data for this Ligand-Target Pair