BDBM50191133 CHEMBL439357::sodium (R)-2-(3-((2-(4,5-diphenyloxazol-2-yl)pyrrolidin-1-yl)methyl)phenoxy)acetate

SMILES: [O-]C(=O)COc1cccc(CN2CCC[C@@H]2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1

InChI Key: InChIKey=WVTUDMXKOFCUFN-XMMPIXPASA-M

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50191133 (CHEMBL439357 | sodium (R)-2-(3-((2-(4,5-diphenylox...) Show SMILES [O-]C(=O)COc1cccc(CN2CCC[C@@H]2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 Show InChI InChI=1S/C28H26N2O4/c31-25(32)19-33-23-14-7-9-20(17-23)18-30-16-8-15-24(30)28-29-26(21-10-3-1-4-11-21)27(34-28)22-12-5-2-6-13-22/h1-7,9-14,17,24H,8,15-16,18-19H2,(H,31,32)/p-1/t24-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]iloprost from cloned human PGI2 receptor				Bioorg Med Chem Lett 16: 4861-4 (2006) Article DOI: 10.1016/j.bmcl.2006.06.076 BindingDB Entry DOI: 10.7270/Q2R49QD9
					More data for this Ligand-Target Pair
PTGIR (RAT)	BDBM50191133 (CHEMBL439357 | sodium (R)-2-(3-((2-(4,5-diphenylox...) Show SMILES [O-]C(=O)COc1cccc(CN2CCC[C@@H]2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 Show InChI InChI=1S/C28H26N2O4/c31-25(32)19-33-23-14-7-9-20(17-23)18-30-16-8-15-24(30)28-29-26(21-10-3-1-4-11-21)27(34-28)22-12-5-2-6-13-22/h1-7,9-14,17,24H,8,15-16,18-19H2,(H,31,32)/p-1/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at rat PGI2 receptor assessed as inhibition of ADP-induced platelet aggregation				Bioorg Med Chem Lett 16: 4861-4 (2006) Article DOI: 10.1016/j.bmcl.2006.06.076 BindingDB Entry DOI: 10.7270/Q2R49QD9
					More data for this Ligand-Target Pair
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50191133 (CHEMBL439357 | sodium (R)-2-(3-((2-(4,5-diphenylox...) Show SMILES [O-]C(=O)COc1cccc(CN2CCC[C@@H]2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 Show InChI InChI=1S/C28H26N2O4/c31-25(32)19-33-23-14-7-9-20(17-23)18-30-16-8-15-24(30)28-29-26(21-10-3-1-4-11-21)27(34-28)22-12-5-2-6-13-22/h1-7,9-14,17,24H,8,15-16,18-19H2,(H,31,32)/p-1/t24-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human PGI2 receptor assessed as inhibition of ADP-induced platelet aggregation				Bioorg Med Chem Lett 16: 4861-4 (2006) Article DOI: 10.1016/j.bmcl.2006.06.076 BindingDB Entry DOI: 10.7270/Q2R49QD9
					More data for this Ligand-Target Pair