BDBM50191520 2-[4-(biphenyl-2-ylmethoxy)-2-methoxyphenyl]-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid::CHEMBL212226

SMILES: COc1cc(OCc2ccccc2-c2ccccc2)ccc1-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O

InChI Key: InChIKey=ZVULSSSMANUZDD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50191520 (2-[4-(biphenyl-2-ylmethoxy)-2-methoxyphenyl]-1-cyc...) Show SMILES COc1cc(OCc2ccccc2-c2ccccc2)ccc1-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O Show InChI InChI=1S/C34H32N2O4/c1-39-32-21-27(40-22-25-12-8-9-15-28(25)23-10-4-2-5-11-23)17-18-29(32)33-35-30-20-24(34(37)38)16-19-31(30)36(33)26-13-6-3-7-14-26/h2,4-5,8-12,15-21,26H,3,6-7,13-14,22H2,1H3,(H,37,38)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymerase				J Med Chem 49: 4721-36 (2006) Article DOI: 10.1021/jm060269e BindingDB Entry DOI: 10.7270/Q2FN15TD
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1)	BDBM50191520 (2-[4-(biphenyl-2-ylmethoxy)-2-methoxyphenyl]-1-cyc...) Show SMILES COc1cc(OCc2ccccc2-c2ccccc2)ccc1-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O Show InChI InChI=1S/C34H32N2O4/c1-39-32-21-27(40-22-25-12-8-9-15-28(25)23-10-4-2-5-11-23)17-18-29(32)33-35-30-20-24(34(37)38)16-19-31(30)36(33)26-13-6-3-7-14-26/h2,4-5,8-12,15-21,26H,3,6-7,13-14,22H2,1H3,(H,37,38)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 min				Citation and Details Article DOI: 10.1007/s00044-012-0186-8 BindingDB Entry DOI: 10.7270/Q2NC6441
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1)	BDBM50191520 (2-[4-(biphenyl-2-ylmethoxy)-2-methoxyphenyl]-1-cyc...) Show SMILES COc1cc(OCc2ccccc2-c2ccccc2)ccc1-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O Show InChI InChI=1S/C34H32N2O4/c1-39-32-21-27(40-22-25-12-8-9-15-28(25)23-10-4-2-5-11-23)17-18-29(32)33-35-30-20-24(34(37)38)16-19-31(30)36(33)26-13-6-3-7-14-26/h2,4-5,8-12,15-21,26H,3,6-7,13-14,22H2,1H3,(H,37,38)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 min				Citation and Details Article DOI: 10.1007/s00044-012-0186-8 BindingDB Entry DOI: 10.7270/Q2NC6441
					More data for this Ligand-Target Pair