BDBM50191526 2-{4-[4-(4-chlorophenyl)-2-methylpyrimidin-5-ylmethoxy]-phenyl}-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid::CHEMBL209921

SMILES: Cc1ncc(COc2ccc(cc2)-c2nc3cc(ccc3n2C2CCCCC2)C(O)=O)c(n1)-c1ccc(Cl)cc1

InChI Key: InChIKey=HWABCDVJANLNTO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50191526 (2-{4-[4-(4-chlorophenyl)-2-methylpyrimidin-5-ylmet...) Show SMILES Cc1ncc(COc2ccc(cc2)-c2nc3cc(ccc3n2C2CCCCC2)C(O)=O)c(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C32H29ClN4O3/c1-20-34-18-24(30(35-20)21-7-12-25(33)13-8-21)19-40-27-14-9-22(10-15-27)31-36-28-17-23(32(38)39)11-16-29(28)37(31)26-5-3-2-4-6-26/h7-18,26H,2-6,19H2,1H3,(H,38,39)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymerase				J Med Chem 49: 4721-36 (2006) Article DOI: 10.1021/jm060269e BindingDB Entry DOI: 10.7270/Q2FN15TD
					More data for this Ligand-Target Pair