BDBM50191528 2-[4-(4-chloro-4'-methylbiphenyl-2-ylmethoxy)phenyl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid::CHEMBL378546

SMILES: Cc1ccc(cc1)-c1ccc(Cl)cc1COc1ccc(cc1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O

InChI Key: InChIKey=YFVKICOQRQSENA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50191528 (2-[4-(4-chloro-4'-methylbiphenyl-2-ylmethoxy)pheny...) Show SMILES Cc1ccc(cc1)-c1ccc(Cl)cc1COc1ccc(cc1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O Show InChI InChI=1S/C34H31ClN2O3/c1-22-7-9-23(10-8-22)30-17-14-27(35)19-26(30)21-40-29-15-11-24(12-16-29)33-36-31-20-25(34(38)39)13-18-32(31)37(33)28-5-3-2-4-6-28/h7-20,28H,2-6,21H2,1H3,(H,38,39)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymerase				J Med Chem 49: 4721-36 (2006) Article DOI: 10.1021/jm060269e BindingDB Entry DOI: 10.7270/Q2FN15TD
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1)	BDBM50191528 (2-[4-(4-chloro-4'-methylbiphenyl-2-ylmethoxy)pheny...) Show SMILES Cc1ccc(cc1)-c1ccc(Cl)cc1COc1ccc(cc1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O Show InChI InChI=1S/C34H31ClN2O3/c1-22-7-9-23(10-8-22)30-17-14-27(35)19-26(30)21-40-29-15-11-24(12-16-29)33-36-31-20-25(34(38)39)13-18-32(31)37(33)28-5-3-2-4-6-28/h7-20,28H,2-6,21H2,1H3,(H,38,39)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 min				Citation and Details Article DOI: 10.1007/s00044-012-0186-8 BindingDB Entry DOI: 10.7270/Q2NC6441
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1)	BDBM50191528 (2-[4-(4-chloro-4'-methylbiphenyl-2-ylmethoxy)pheny...) Show SMILES Cc1ccc(cc1)-c1ccc(Cl)cc1COc1ccc(cc1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O Show InChI InChI=1S/C34H31ClN2O3/c1-22-7-9-23(10-8-22)30-17-14-27(35)19-26(30)21-40-29-15-11-24(12-16-29)33-36-31-20-25(34(38)39)13-18-32(31)37(33)28-5-3-2-4-6-28/h7-20,28H,2-6,21H2,1H3,(H,38,39)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.02E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 min				Citation and Details Article DOI: 10.1007/s00044-012-0186-8 BindingDB Entry DOI: 10.7270/Q2NC6441
					More data for this Ligand-Target Pair