BDBM50191553 (S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide::CHEMBL209789

SMILES: [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1

InChI Key: InChIKey=HTSRDLNRKNCSLJ-XFBWMNOSSA-N

Data: 3 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50191553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191553 ((S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinop...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C35H45N7O5/c1-23(43)40-30(15-16-32(36)44)33(45)41-31(19-24-8-3-2-4-9-24)34(46)42-21-29(20-28(42)12-7-17-39-35(37)38)47-22-25-13-14-26-10-5-6-11-27(26)18-25/h2-6,8-11,13-14,18,28-31H,7,12,15-17,19-22H2,1H3,(H2,36,44)(H,40,43)(H,41,45)(H4,37,38,39)/t28-,29+,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50191553 ((S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinop...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C35H45N7O5/c1-23(43)40-30(15-16-32(36)44)33(45)41-31(19-24-8-3-2-4-9-24)34(46)42-21-29(20-28(42)12-7-17-39-35(37)38)47-22-25-13-14-26-10-5-6-11-27(26)18-25/h2-6,8-11,13-14,18,28-31H,7,12,15-17,19-22H2,1H3,(H2,36,44)(H,40,43)(H,41,45)(H4,37,38,39)/t28-,29+,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50191553 ((S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinop...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C35H45N7O5/c1-23(43)40-30(15-16-32(36)44)33(45)41-31(19-24-8-3-2-4-9-24)34(46)42-21-29(20-28(42)12-7-17-39-35(37)38)47-22-25-13-14-26-10-5-6-11-27(26)18-25/h2-6,8-11,13-14,18,28-31H,7,12,15-17,19-22H2,1H3,(H2,36,44)(H,40,43)(H,41,45)(H4,37,38,39)/t28-,29+,30-,31+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191553 ((S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinop...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C35H45N7O5/c1-23(43)40-30(15-16-32(36)44)33(45)41-31(19-24-8-3-2-4-9-24)34(46)42-21-29(20-28(42)12-7-17-39-35(37)38)47-22-25-13-14-26-10-5-6-11-27(26)18-25/h2-6,8-11,13-14,18,28-31H,7,12,15-17,19-22H2,1H3,(H2,36,44)(H,40,43)(H,41,45)(H4,37,38,39)/t28-,29+,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC4R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50191553 ((S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinop...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C35H45N7O5/c1-23(43)40-30(15-16-32(36)44)33(45)41-31(19-24-8-3-2-4-9-24)34(46)42-21-29(20-28(42)12-7-17-39-35(37)38)47-22-25-13-14-26-10-5-6-11-27(26)18-25/h2-6,8-11,13-14,18,28-31H,7,12,15-17,19-22H2,1H3,(H2,36,44)(H,40,43)(H,41,45)(H4,37,38,39)/t28-,29+,30-,31+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC3R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50191553 ((S)-2-acetamido-N1-((R)-1-((2S,4R)-2-(3-guanidinop...) Show SMILES [#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C35H45N7O5/c1-23(43)40-30(15-16-32(36)44)33(45)41-31(19-24-8-3-2-4-9-24)34(46)42-21-29(20-28(42)12-7-17-39-35(37)38)47-22-25-13-14-26-10-5-6-11-27(26)18-25/h2-6,8-11,13-14,18,28-31H,7,12,15-17,19-22H2,1H3,(H2,36,44)(H,40,43)(H,41,45)(H4,37,38,39)/t28-,29+,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC1R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair