BDBM50191913 CHEMBL384350::N-(2-methyl-4-(2-(pyrrolidin-1-yl)ethyl)phenyl)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine

SMILES: Cc1cc(CCN2CCCC2)ccc1Nc1nccc(n1)-c1c[nH]c2ncccc12

InChI Key: InChIKey=UCSGBFLLOMEVMS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3 (Homo sapiens (Human))	BDBM50191913 (CHEMBL384350 | N-(2-methyl-4-(2-(pyrrolidin-1-yl)e...) Show SMILES Cc1cc(CCN2CCCC2)ccc1Nc1nccc(n1)-c1c[nH]c2ncccc12 Show InChI InChI=1S/C24H26N6/c1-17-15-18(9-14-30-12-2-3-13-30)6-7-21(17)28-24-26-11-8-22(29-24)20-16-27-23-19(20)5-4-10-25-23/h4-8,10-11,15-16H,2-3,9,12-14H2,1H3,(H,25,27)(H,26,28,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclinB by Flashplate assay				Bioorg Med Chem Lett 16: 4818-21 (2006) Article DOI: 10.1016/j.bmcl.2006.06.073 BindingDB Entry DOI: 10.7270/Q2571BNM
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