BDBM50191941 CHEMBL1761586
SMILES: Cc1ccc2NC(=O)\C(=N/N=C3\SCC(=O)N3c3ccc(O)cc3)c2c1
InChI Key: InChIKey=LLKKVBMKUPHBOE-UZYVYHOESA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (Homo sapiens (Human)) | BDBM50191941 (CHEMBL1761586) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Myrexis, Inc. Curated by ChEMBL | Assay Description Competitive inhibition of recombinant TAK1-TAB1 assessed as [33P]gamma-ATP incorporation into substrate histone H1 peptide by filter plate assay | Bioorg Med Chem Lett 21: 1724-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.077 BindingDB Entry DOI: 10.7270/Q2988794 | |||||||||||
More data for this Ligand-Target Pair |