null
SMILES: CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(C)=O)C(C)C)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O
InChI Key: InChIKey=YSBLDQMUSOQJJY-PVGXKDMPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukocyte surface antigen CD47 (Homo sapiens (Human)) | BDBM50192014 (CHEMBL3891508) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a |
Sorbonne Universit£s Curated by ChEMBL | Assay Description Binding affinity to CD47 receptor in human biotinylated MEC1 cell membranes by biolayer interferometry | J Med Chem 59: 8412-21 (2016) BindingDB Entry DOI: 10.7270/Q2251M4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukocyte surface antigen CD47 (Homo sapiens (Human)) | BDBM50192014 (CHEMBL3891508) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a |
Sorbonne Universit£s Curated by ChEMBL | Assay Description Binding affinity to CD47 receptor in human NT.115-labeled MEC1 cell membranes after 5 mins by MST assay | J Med Chem 59: 8412-21 (2016) BindingDB Entry DOI: 10.7270/Q2251M4K | |||||||||||
More data for this Ligand-Target Pair |