BDBM50192036 Ac-Phe-[Orn-Pro-cha-Trp-Hle]::CHEMBL435921

SMILES: CC(C)CC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O

InChI Key: InChIKey=LOZDPFBVQFEVJZ-PHHHQBPDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50192036 (Ac-Phe-[Orn-Pro-cha-Trp-Hle] | CHEMBL435921) Show SMILES CC(C)CC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O Show InChI InChI=1S/C48H66N8O7/c1-30(2)22-23-37-43(58)49-24-12-20-38(53-44(59)39(51-31(3)57)26-32-14-6-4-7-15-32)48(63)56-25-13-21-42(56)47(62)55-40(27-33-16-8-5-9-17-33)45(60)54-41(46(61)52-37)28-34-29-50-36-19-11-10-18-35(34)36/h4,6-7,10-11,14-15,18-19,29-30,33,37-42,50H,5,8-9,12-13,16-17,20-28H2,1-3H3,(H,49,58)(H,51,57)(H,52,61)(H,53,59)(H,54,60)(H,55,62)/t37-,38-,39-,40+,41-,42-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Jerini AG Curated by ChEMBL					Assay Description Antagonist activity at human C5aR in CD88 transfected RBL cells assessed as inhibition of C5a-induced glucosaminidase release				Bioorg Med Chem Lett 16: 5088-92 (2006) Article DOI: 10.1016/j.bmcl.2006.07.036 BindingDB Entry DOI: 10.7270/Q2RX9BP8
					More data for this Ligand-Target Pair