BDBM50192051 Ac-Phe-[Orn-Pro-cha-Trp-Nle]::CHEMBL374575

SMILES: CCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O

InChI Key: InChIKey=DZLHHFMBZAYQCZ-ZQPNNPFBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50192051 (Ac-Phe-[Orn-Pro-cha-Trp-Nle] | CHEMBL374575) Show SMILES CCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O Show InChI InChI=1S/C47H64N8O7/c1-3-4-20-36-42(57)48-24-13-22-37(52-43(58)38(50-30(2)56)26-31-15-7-5-8-16-31)47(62)55-25-14-23-41(55)46(61)54-39(27-32-17-9-6-10-18-32)44(59)53-40(45(60)51-36)28-33-29-49-35-21-12-11-19-34(33)35/h5,7-8,11-12,15-16,19,21,29,32,36-41,49H,3-4,6,9-10,13-14,17-18,20,22-28H2,1-2H3,(H,48,57)(H,50,56)(H,51,60)(H,52,58)(H,53,59)(H,54,61)/t36-,37-,38-,39+,40-,41-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Jerini AG Curated by ChEMBL					Assay Description Antagonist activity at human C5aR in CD88 transfected RBL cells assessed as inhibition of C5a-induced glucosaminidase release				Bioorg Med Chem Lett 16: 5088-92 (2006) Article DOI: 10.1016/j.bmcl.2006.07.036 BindingDB Entry DOI: 10.7270/Q2RX9BP8
					More data for this Ligand-Target Pair