BDBM50192056 Ac-Phe-[Orn-Pro-cha-Trp-Nva]::CHEMBL412031

SMILES: CCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O

InChI Key: InChIKey=QAEBVSMKCRETFQ-HPSWDUTRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50192056 (Ac-Phe-[Orn-Pro-cha-Trp-Nva] | CHEMBL412031) Show SMILES CCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O Show InChI InChI=1S/C46H62N8O7/c1-3-14-35-41(56)47-23-12-21-36(51-42(57)37(49-29(2)55)25-30-15-6-4-7-16-30)46(61)54-24-13-22-40(54)45(60)53-38(26-31-17-8-5-9-18-31)43(58)52-39(44(59)50-35)27-32-28-48-34-20-11-10-19-33(32)34/h4,6-7,10-11,15-16,19-20,28,31,35-40,48H,3,5,8-9,12-14,17-18,21-27H2,1-2H3,(H,47,56)(H,49,55)(H,50,59)(H,51,57)(H,52,58)(H,53,60)/t35-,36-,37-,38+,39-,40-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Jerini AG Curated by ChEMBL					Assay Description Antagonist activity at human C5aR in CD88 transfected RBL cells assessed as inhibition of C5a-induced glucosaminidase release				Bioorg Med Chem Lett 16: 5088-92 (2006) Article DOI: 10.1016/j.bmcl.2006.07.036 BindingDB Entry DOI: 10.7270/Q2RX9BP8
					More data for this Ligand-Target Pair