BDBM50192064 Ac-Phe-[Orn-Pro-cha-Trp-Hch]::CHEMBL219386

SMILES: CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCNC(=O)[C@H](CCC2CCCCC2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O

InChI Key: InChIKey=UANWIBIMCWBUBW-CPPKSIGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50192064 (Ac-Phe-[Orn-Pro-cha-Trp-Hch] | CHEMBL219386) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCNC(=O)[C@H](CCC2CCCCC2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O Show InChI InChI=1S/C51H70N8O7/c1-33(60)54-42(29-35-17-7-3-8-18-35)47(62)56-41-23-13-27-52-46(61)40(26-25-34-15-5-2-6-16-34)55-49(64)44(31-37-32-53-39-22-12-11-21-38(37)39)57-48(63)43(30-36-19-9-4-10-20-36)58-50(65)45-24-14-28-59(45)51(41)66/h3,7-8,11-12,17-18,21-22,32,34,36,40-45,53H,2,4-6,9-10,13-16,19-20,23-31H2,1H3,(H,52,61)(H,54,60)(H,55,64)(H,56,62)(H,57,63)(H,58,65)/t40-,41-,42-,43+,44-,45-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Jerini AG Curated by ChEMBL					Assay Description Antagonist activity at human C5aR in CD88 transfected RBL cells assessed as inhibition of C5a-induced glucosaminidase release				Bioorg Med Chem Lett 16: 5088-92 (2006) Article DOI: 10.1016/j.bmcl.2006.07.036 BindingDB Entry DOI: 10.7270/Q2RX9BP8
					More data for this Ligand-Target Pair