BDBM50192066 Ac-Phe-[Orn-Pro-cha-Trp-Chg]::CHEMBL374717

SMILES: CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCNC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O)C1CCCCC1

InChI Key: InChIKey=QOCOPNWXTXIJOK-WKSNNGRJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM50192066 (Ac-Phe-[Orn-Pro-cha-Trp-Chg] | CHEMBL374717) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCNC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O)C1CCCCC1 Show InChI InChI=1S/C49H66N8O7/c1-31(58)52-39(27-32-15-5-2-6-16-32)44(59)53-38-23-13-25-50-48(63)43(34-19-9-4-10-20-34)56-46(61)41(29-35-30-51-37-22-12-11-21-36(35)37)54-45(60)40(28-33-17-7-3-8-18-33)55-47(62)42-24-14-26-57(42)49(38)64/h2,5-6,11-12,15-16,21-22,30,33-34,38-43,51H,3-4,7-10,13-14,17-20,23-29H2,1H3,(H,50,63)(H,52,58)(H,53,59)(H,54,60)(H,55,62)(H,56,61)/t38-,39-,40+,41-,42-,43-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Jerini AG Curated by ChEMBL					Assay Description Antagonist activity at human C5aR in CD88 transfected RBL cells assessed as inhibition of C5a-induced glucosaminidase release				Bioorg Med Chem Lett 16: 5088-92 (2006) Article DOI: 10.1016/j.bmcl.2006.07.036 BindingDB Entry DOI: 10.7270/Q2RX9BP8
					More data for this Ligand-Target Pair