BDBM50192078 9-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-1,2,3,9b-tetrahydro-pyrrolo[2,1-a]isoindol-5-one::CHEMBL425438

SMILES: O=C1N2CCCC2c2c1cccc2N1Cc2ccccc2NC1=O

InChI Key: InChIKey=DIZPSQQGONUJBE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50192078 (9-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-1,2,3,9b-...) Show SMILES O=C1N2CCCC2c2c1cccc2N1Cc2ccccc2NC1=O Show InChI InChI=1S/C19H17N3O2/c23-18-13-6-3-8-16(17(13)15-9-4-10-21(15)18)22-11-12-5-1-2-7-14(12)20-19(22)24/h1-3,5-8,15H,4,9-11H2,(H,20,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CDK4				Bioorg Med Chem Lett 16: 5122-6 (2006) Article DOI: 10.1016/j.bmcl.2006.07.026 BindingDB Entry DOI: 10.7270/Q2K35VF0
					More data for this Ligand-Target Pair