BDBM50192369 3,9-dihydroxy-4-phenyl-2,3-dihydropyrrolo[3,4-c]carbazol-1(6H)-one::3,9-dihydroxy-4-phenyl-3,6-dihydropyrrolo[3,4-c]carbazol-1(2H)-one::CHEMBL378766

SMILES: OC1NC(=O)c2c1c(cc1[nH]c3ccc(O)cc3c21)-c1ccccc1

InChI Key: InChIKey=PWRZMTICBBEOSA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50192369 (3,9-dihydroxy-4-phenyl-2,3-dihydropyrrolo[3,4-c]ca...) Show SMILES OC1NC(=O)c2c1c(cc1[nH]c3ccc(O)cc3c21)-c1ccccc1 Show InChI InChI=1S/C20H14N2O3/c23-11-6-7-14-13(8-11)16-15(21-14)9-12(10-4-2-1-3-5-10)17-18(16)20(25)22-19(17)24/h1-9,19,21,23-24H,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of human Wee1 in presence of 9.5 uM ATP				J Med Chem 49: 4896-911 (2006) Article DOI: 10.1021/jm0512591 BindingDB Entry DOI: 10.7270/Q23778BD
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50192369 (3,9-dihydroxy-4-phenyl-2,3-dihydropyrrolo[3,4-c]ca...) Show SMILES OC1NC(=O)c2c1c(cc1[nH]c3ccc(O)cc3c21)-c1ccccc1 Show InChI InChI=1S/C20H14N2O3/c23-11-6-7-14-13(8-11)16-15(21-14)9-12(10-4-2-1-3-5-10)17-18(16)20(25)22-19(17)24/h1-9,19,21,23-24H,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition at human Chk1 in presence of 4 uM ATP				J Med Chem 49: 4896-911 (2006) Article DOI: 10.1021/jm0512591 BindingDB Entry DOI: 10.7270/Q23778BD
					More data for this Ligand-Target Pair