BDBM50192405 2-amino-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::2-amino-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3-(2H,6H)-dione::CHEMBL212933

SMILES: NN1C(=O)c2c(C1=O)c1c(cc2-c2ccccc2)[nH]c2ccc(O)cc12

InChI Key: InChIKey=LHVHZMHTSVKYGK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50192405 (2-amino-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-...) Show SMILES NN1C(=O)c2c(C1=O)c1c(cc2-c2ccccc2)[nH]c2ccc(O)cc12 Show InChI InChI=1S/C20H13N3O3/c21-23-19(25)17-12(10-4-2-1-3-5-10)9-15-16(18(17)20(23)26)13-8-11(24)6-7-14(13)22-15/h1-9,22,24H,21H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition at human Chk1 in presence of 4 uM ATP				J Med Chem 49: 4896-911 (2006) Article DOI: 10.1021/jm0512591 BindingDB Entry DOI: 10.7270/Q23778BD
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50192405 (2-amino-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-...) Show SMILES NN1C(=O)c2c(C1=O)c1c(cc2-c2ccccc2)[nH]c2ccc(O)cc12 Show InChI InChI=1S/C20H13N3O3/c21-23-19(25)17-12(10-4-2-1-3-5-10)9-15-16(18(17)20(23)26)13-8-11(24)6-7-14(13)22-15/h1-9,22,24H,21H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of human Wee1				Eur J Med Chem 44: 1383-95 (2009) Article DOI: 10.1016/j.ejmech.2008.09.027 BindingDB Entry DOI: 10.7270/Q2X34XB6
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50192405 (2-amino-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-...) Show SMILES NN1C(=O)c2c(C1=O)c1c(cc2-c2ccccc2)[nH]c2ccc(O)cc12 Show InChI InChI=1S/C20H13N3O3/c21-23-19(25)17-12(10-4-2-1-3-5-10)9-15-16(18(17)20(23)26)13-8-11(24)6-7-14(13)22-15/h1-9,22,24H,21H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of human Wee1 in presence of 9.5 uM ATP				J Med Chem 49: 4896-911 (2006) Article DOI: 10.1021/jm0512591 BindingDB Entry DOI: 10.7270/Q23778BD
					More data for this Ligand-Target Pair