null
SMILES: COc1ccc(cc1)[C@]1(CCO)CC(=NN1C(=O)Nc1ccc(Br)cc1)c1cccnc1
InChI Key: InChIKey=FKUVJZGPXYCCEB-DEOSSOPVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human)) | BDBM50192688 (CHEMBL3928071) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Actelion Pharmaceuticals Ltd. Curated by ChEMBL | Assay Description Inhibition of human T-type calcium channel Cav3.2 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential m... | J Med Chem 59: 8398-411 (2016) BindingDB Entry DOI: 10.7270/Q2J67JWK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human)) | BDBM50192688 (CHEMBL3928071) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Actelion Pharmaceuticals Ltd. Curated by ChEMBL | Assay Description Inhibition of recombinant T-type calcium channel Cav1.2 (unknown origin) expressed in HEK293 cells assessed as inhibition of Kcl-induced calcium infl... | J Med Chem 59: 8398-411 (2016) BindingDB Entry DOI: 10.7270/Q2J67JWK | |||||||||||
More data for this Ligand-Target Pair |