BDBM50192697 CHEMBL3969020

SMILES: Fc1ccc(cc1)C1CC(=NN1C(=O)Nc1ccccn1)c1ccc(Br)cc1

InChI Key: InChIKey=HBXXOZGTEHENQK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM50192697 (CHEMBL3969020) Show SMILES Fc1ccc(cc1)C1CC(=NN1C(=O)Nc1ccccn1)c1ccc(Br)cc1 |c:10| Show InChI InChI=1S/C21H16BrFN4O/c22-16-8-4-14(5-9-16)18-13-19(15-6-10-17(23)11-7-15)27(26-18)21(28)25-20-3-1-2-12-24-20/h1-12,19H,13H2,(H,24,25,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	393	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant T-type calcium channel Cav3.2 (unknown origin) expressed in HEK293 cells assessed as inhibition of CaCl2-induced calcium in...				J Med Chem 59: 8398-411 (2016) BindingDB Entry DOI: 10.7270/Q2J67JWK
					More data for this Ligand-Target Pair
Voltage-gated calcium channel (Homo sapiens (Human))	BDBM50192697 (CHEMBL3969020) Show SMILES Fc1ccc(cc1)C1CC(=NN1C(=O)Nc1ccccn1)c1ccc(Br)cc1 |c:10| Show InChI InChI=1S/C21H16BrFN4O/c22-16-8-4-14(5-9-16)18-13-19(15-6-10-17(23)11-7-15)27(26-18)21(28)25-20-3-1-2-12-24-20/h1-12,19H,13H2,(H,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant T-type calcium channel Cav1.2 (unknown origin) expressed in HEK293 cells assessed as inhibition of Kcl-induced calcium infl...				J Med Chem 59: 8398-411 (2016) BindingDB Entry DOI: 10.7270/Q2J67JWK
					More data for this Ligand-Target Pair