BDBM50192714 1-(4-methoxyphenyl)-3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}urea::CHEMBL218201

SMILES: CCCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12

InChI Key: InChIKey=XCSJZQINTSVQMV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192714 (1-(4-methoxyphenyl)-3-{19-methyl-14-oxo-3-propyl-3...) Show SMILES CCCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C31H30N6O3/c1-4-13-37-25-12-7-18(34-31(39)33-17-5-8-19(40-3)9-6-17)14-21(25)27-22-15-32-30(38)28(22)26-20(29(27)37)10-11-24-23(26)16-36(2)35-24/h5-9,12,14,16H,4,10-11,13,15H2,1-3H3,(H,32,38)(H2,33,34,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 16: 5368-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.066 BindingDB Entry DOI: 10.7270/Q2SQ901V
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50192714 (1-(4-methoxyphenyl)-3-{19-methyl-14-oxo-3-propyl-3...) Show SMILES CCCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C31H30N6O3/c1-4-13-37-25-12-7-18(34-31(39)33-17-5-8-19(40-3)9-6-17)14-21(25)27-22-15-32-30(38)28(22)26-20(29(27)37)10-11-24-23(26)16-36(2)35-24/h5-9,12,14,16H,4,10-11,13,15H2,1-3H3,(H,32,38)(H2,33,34,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of Tie2				Bioorg Med Chem Lett 16: 5368-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.066 BindingDB Entry DOI: 10.7270/Q2SQ901V
					More data for this Ligand-Target Pair