BDBM50192722 1-(4-fluorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl}urea::CHEMBL374745

SMILES: CCCn1c2ccc(NC(=O)Nc3ccc(F)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12

InChI Key: InChIKey=ALAMKIQLXIWFRA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50192722 (1-(4-fluorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,...) Show SMILES CCCn1c2ccc(NC(=O)Nc3ccc(F)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C30H27FN6O2/c1-3-12-37-24-11-8-18(34-30(39)33-17-6-4-16(31)5-7-17)13-20(24)26-21-14-32-29(38)27(21)25-19(28(26)37)9-10-23-22(25)15-36(2)35-23/h4-8,11,13,15H,3,9-10,12,14H2,1-2H3,(H,32,38)(H2,33,34,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 16: 5368-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.066 BindingDB Entry DOI: 10.7270/Q2SQ901V
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50192722 (1-(4-fluorophenyl)-3-{19-methyl-14-oxo-3-propyl-3,...) Show SMILES CCCn1c2ccc(NC(=O)Nc3ccc(F)cc3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C30H27FN6O2/c1-3-12-37-24-11-8-18(34-30(39)33-17-6-4-16(31)5-7-17)13-20(24)26-21-14-32-29(38)27(21)25-19(28(26)37)9-10-23-22(25)15-36(2)35-23/h4-8,11,13,15H,3,9-10,12,14H2,1-2H3,(H,32,38)(H2,33,34,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of Tie2				Bioorg Med Chem Lett 16: 5368-72 (2006) Article DOI: 10.1016/j.bmcl.2006.07.066 BindingDB Entry DOI: 10.7270/Q2SQ901V
					More data for this Ligand-Target Pair