null

SMILES: [H][C@]12CC[C@]([H])(C\C(C1)=N/OC1CCN(C)CC1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

InChI Key: InChIKey=MDQOBEHUFJIXIQ-CARBOWHASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50192828 (CHEMBL3914089) Show SMILES [H][C@]12CC[C@]([H])(C\C(C1)=N/OC1CCN(C)CC1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r| Show InChI InChI=1S/C27H33N7O2S2/c1-16-25(38-17(2)29-16)23-15-37-27(30-23)31-24-7-4-18(14-28-24)26(35)34-20-5-6-21(34)13-19(12-20)32-36-22-8-10-33(3)11-9-22/h4,7,14-15,20-22H,5-6,8-13H2,1-3H3,(H,28,30,31)/b32-19-/t20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi& Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activation				Bioorg Med Chem Lett 26: 4936-4941 (2016) Article DOI: 10.1016/j.bmcl.2016.09.014 BindingDB Entry DOI: 10.7270/Q2154K06
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50192828 (CHEMBL3914089) Show SMILES [H][C@]12CC[C@]([H])(C\C(C1)=N/OC1CCN(C)CC1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1 |r| Show InChI InChI=1S/C27H33N7O2S2/c1-16-25(38-17(2)29-16)23-15-37-27(30-23)31-24-7-4-18(14-28-24)26(35)34-20-5-6-21(34)13-19(12-20)32-36-22-8-10-33(3)11-9-22/h4,7,14-15,20-22H,5-6,8-13H2,1-3H3,(H,28,30,31)/b32-19-/t20-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi& Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activation				Bioorg Med Chem Lett 26: 4936-4941 (2016) Article DOI: 10.1016/j.bmcl.2016.09.014 BindingDB Entry DOI: 10.7270/Q2154K06
					More data for this Ligand-Target Pair