Found 3 hits for monomerid = 50192846 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50192846
(CHEMBL3358992)Show SMILES COc1cccc(c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H20N2O5/c1-24-14-7-5-6-12(8-14)15-11-21-20(23)18(22-15)13-9-16(25-2)19(27-4)17(10-13)26-3/h5-11H,1-4H3,(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Christian-Albrechts-University of Kiel
Curated by ChEMBL
| Assay Description Inhibition of human c-KiT |
J Med Chem 58: 170-82 (2015)
Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50192846
(CHEMBL3358992)Show SMILES COc1cccc(c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H20N2O5/c1-24-14-7-5-6-12(8-14)15-11-21-20(23)18(22-15)13-9-16(25-2)19(27-4)17(10-13)26-3/h5-11H,1-4H3,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Christian-Albrechts-University of Kiel
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate |
J Med Chem 58: 170-82 (2015)
Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50192846
(CHEMBL3358992)Show SMILES COc1cccc(c1)-c1c[nH]c(=O)c(n1)-c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C20H20N2O5/c1-24-14-7-5-6-12(8-14)15-11-21-20(23)18(22-15)13-9-16(25-2)19(27-4)17(10-13)26-3/h5-11H,1-4H3,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Christian-Albrechts-University of Kiel
Curated by ChEMBL
| Assay Description Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrate |
J Med Chem 58: 170-82 (2015)
Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R |
More data for this Ligand-Target Pair | |