BDBM50192876 CHEMBL3358978

SMILES: COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccc(C)cc12

InChI Key: InChIKey=BAJXJKMGTOHSDZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50192876 (CHEMBL3358978) Show SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccc(C)cc12 Show InChI InChI=1S/C22H21N3O4/c1-12-5-6-16-14(7-12)15(10-23-16)17-11-24-22(26)20(25-17)13-8-18(27-2)21(29-4)19(9-13)28-3/h5-11,23H,1-4H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrate				J Med Chem 58: 170-82 (2015) Article DOI: 10.1021/jm500373x BindingDB Entry DOI: 10.7270/Q2ZG6V0R
					More data for this Ligand-Target Pair