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Enter Data

BDBM50192906 8S-hydroxylobel-9-ene::CHEMBL213613

SMILES: CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1

InChI Key: InChIKey=IKYXUFYHDWVXST-HTNBDEJSSA-N

Data: 3 KI 2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50192906
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50192906 (8S-hydroxylobel-9-ene \| CHEMBL213613) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes				Bioorg Med Chem Lett 16: 5018-21 (2006) Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK
University of Kentucky Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50192906 (8S-hydroxylobel-9-ene \| CHEMBL213613) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes				Bioorg Med Chem Lett 16: 5018-21 (2006) Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK
University of Kentucky Curated by ChEMBL					More data for this Ligand-Target Pair
Vesicular monoamine transporter 2 (VMAT2) (Rattus norvegicus (Rat))	BDBM50192906 (8S-hydroxylobel-9-ene \| CHEMBL213613) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane				Bioorg Med Chem Lett 16: 5018-21 (2006) Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK
University of Kentucky Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50192906 (8S-hydroxylobel-9-ene \| CHEMBL213613) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane				Bioorg Med Chem Lett 16: 5018-21 (2006) Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK
University of Kentucky Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50192906 (8S-hydroxylobel-9-ene \| CHEMBL213613) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane				Bioorg Med Chem Lett 16: 5018-21 (2006) Article DOI: 10.1016/j.bmcl.2006.07.070 BindingDB Entry DOI: 10.7270/Q2513XTK
University of Kentucky Curated by ChEMBL					More data for this Ligand-Target Pair