BDBM50193060 3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic acid::CHEMBL216000
SMILES: OC(=O)c1ccc2c(C3CCCCC3)c([nH]c2c1)-c1ccoc1
InChI Key: InChIKey=JTBGUPHSMQLZDS-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-directed RNA polymerase II subunit RPB1 (Homo sapiens (Human)) | BDBM50193060 (3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Curated by ChEMBL | Assay Description Inhibition of calf thymus DNA dependent RNA polymerase 2 | Bioorg Med Chem Lett 16: 4987-93 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.07.074 BindingDB Entry DOI: 10.7270/Q27S7PJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Poliovirus type 1 polyprotein (Poliovirus type 1 (strain Mahoney)) | BDBM50193060 (3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Curated by ChEMBL | Assay Description Inhibition of poliovirus RNA dependent RNA polymerase | Bioorg Med Chem Lett 16: 4987-93 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.07.074 BindingDB Entry DOI: 10.7270/Q27S7PJT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus) | BDBM50193060 (3-cyclohexyl-2-(furan-3-yl)-1H-indole-6-carboxylic...) | UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Curated by ChEMBL | Assay Description Inhibition of HCV 1b NS5B delta21 RNA dependent RNA polymerase by SPA | Bioorg Med Chem Lett 16: 4987-93 (2006) Checked by Author Article DOI: 10.1016/j.bmcl.2006.07.074 BindingDB Entry DOI: 10.7270/Q27S7PJT | |||||||||||
More data for this Ligand-Target Pair |