BDBM50193115 CHEMBL3945656

SMILES: Cl.CC1=CC(=O)N(Nc2nc(nc3sc(c(C)c23)-c2ccc(OCCN3CCCC3)cc2)-c2cccs2)C1=O

InChI Key: InChIKey=LXDPKUDVTRBFBT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50193115 (CHEMBL3945656) Show SMILES Cl.CC1=CC(=O)N(Nc2nc(nc3sc(c(C)c23)-c2ccc(OCCN3CCCC3)cc2)-c2cccs2)C1=O |t:1| Show InChI InChI=1S/C28H27N5O3S2.ClH/c1-17-16-22(34)33(28(17)35)31-26-23-18(2)24(38-27(23)30-25(29-26)21-6-5-15-37-21)19-7-9-20(10-8-19)36-14-13-32-11-3-4-12-32;/h5-10,15-16H,3-4,11-14H2,1-2H3,(H,29,30,31);1H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 expressed in insect Sf21 cells preincubated for 15 mins followed by poly(Glu:Tyr) substrate addition for 30 mins...				Eur J Med Chem 120: 74-85 (2016) Article DOI: 10.1016/j.ejmech.2016.05.022 BindingDB Entry DOI: 10.7270/Q2BG2QX3
					More data for this Ligand-Target Pair