BDBM50193116 CHEMBL3936771

SMILES: Cl.CC1=CC(=O)N(Nc2nc(nc3sc(c(C)c23)-c2ccc(OCCNCCO)cc2)-c2cccs2)C1=O

InChI Key: InChIKey=GYYQOBSXWXWLRW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50193116 (CHEMBL3936771) Show SMILES Cl.CC1=CC(=O)N(Nc2nc(nc3sc(c(C)c23)-c2ccc(OCCNCCO)cc2)-c2cccs2)C1=O |t:1| Show InChI InChI=1S/C26H25N5O4S2.ClH/c1-15-14-20(33)31(26(15)34)30-24-21-16(2)22(37-25(21)29-23(28-24)19-4-3-13-36-19)17-5-7-18(8-6-17)35-12-10-27-9-11-32;/h3-8,13-14,27,32H,9-12H2,1-2H3,(H,28,29,30);1H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 expressed in insect Sf21 cells preincubated for 15 mins followed by poly(Glu:Tyr) substrate addition for 30 mins...				Eur J Med Chem 120: 74-85 (2016) Article DOI: 10.1016/j.ejmech.2016.05.022 BindingDB Entry DOI: 10.7270/Q2BG2QX3
					More data for this Ligand-Target Pair