BDBM50193222 2-{[(1R)-1-[(2-{[(4-carbamimidoylphenyl)methyl]carbamoyl}-2,3-dihydro-1H-inden-2-yl)carbamoyl]propyl]amino}acetic acid::CHEMBL212971

SMILES: CC[C@@H](NCC(O)=O)C(=O)NC1(Cc2ccccc2C1)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key: InChIKey=KAPKZRFHRNMZAJ-LJQANCHMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50193222 (2-{[(1R)-1-[(2-{[(4-carbamimidoylphenyl)methyl]car...) Show SMILES CC[C@@H](NCC(O)=O)C(=O)NC1(Cc2ccccc2C1)C(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C24H29N5O4/c1-2-19(27-14-20(30)31)22(32)29-24(11-17-5-3-4-6-18(17)12-24)23(33)28-13-15-7-9-16(10-8-15)21(25)26/h3-10,19,27H,2,11-14H2,1H3,(H3,25,26)(H,28,33)(H,29,32)(H,30,31)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of human thrombin activity				J Med Chem 49: 5047-50 (2006) Article DOI: 10.1021/jm0606950 BindingDB Entry DOI: 10.7270/Q2H994VN
					More data for this Ligand-Target Pair
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50193222 (2-{[(1R)-1-[(2-{[(4-carbamimidoylphenyl)methyl]car...) Show SMILES CC[C@@H](NCC(O)=O)C(=O)NC1(Cc2ccccc2C1)C(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C24H29N5O4/c1-2-19(27-14-20(30)31)22(32)29-24(11-17-5-3-4-6-18(17)12-24)23(33)28-13-15-7-9-16(10-8-15)21(25)26/h3-10,19,27H,2,11-14H2,1H3,(H3,25,26)(H,28,33)(H,29,32)(H,30,31)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of human aPC				J Med Chem 49: 5047-50 (2006) Article DOI: 10.1021/jm0606950 BindingDB Entry DOI: 10.7270/Q2H994VN
					More data for this Ligand-Target Pair