BDBM50193223 CHEMBL212786::{(R)-1-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2,2-diphenyl-ethylcarbamoyl]-2-methyl-propylamino}-acetic acid

SMILES: CC(C)[C@@H](NCC(O)=O)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key: InChIKey=SMNTXTQPDXQYIC-SXOMAYOGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50193223 (CHEMBL212786 | {(R)-1-[(S)-1-(4-carbamimidoyl-benz...) Show SMILES CC(C)[C@@H](NCC(O)=O)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C30H35N5O4/c1-19(2)26(33-18-24(36)37)30(39)35-27(29(38)34-17-20-13-15-23(16-14-20)28(31)32)25(21-9-5-3-6-10-21)22-11-7-4-8-12-22/h3-16,19,25-27,33H,17-18H2,1-2H3,(H3,31,32)(H,34,38)(H,35,39)(H,36,37)/t26-,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of human aPC				J Med Chem 49: 5047-50 (2006) Article DOI: 10.1021/jm0606950 BindingDB Entry DOI: 10.7270/Q2H994VN
					More data for this Ligand-Target Pair