BDBM50193225 CHEMBL424882::{(R)-1-[6-(4-carbamimidoyl-benzylcarbamoyl)-6,7-dihydro-5H-dibenzo[a,c]cyclohepten-6-ylcarbamoyl]-2-methyl-propylamino}-acetic acid

SMILES: CC(C)[C@@H](NCC(O)=O)C(=O)NC1(Cc2ccccc2-c2ccccc2C1)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key: InChIKey=CVLTZWVWHRNSEJ-HHHXNRCGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50193225 (CHEMBL424882 | {(R)-1-[6-(4-carbamimidoyl-benzylca...) Show SMILES CC(C)[C@@H](NCC(O)=O)C(=O)NC1(Cc2ccccc2-c2ccccc2C1)C(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C31H35N5O4/c1-19(2)27(34-18-26(37)38)29(39)36-31(30(40)35-17-20-11-13-21(14-12-20)28(32)33)15-22-7-3-5-9-24(22)25-10-6-4-8-23(25)16-31/h3-14,19,27,34H,15-18H2,1-2H3,(H3,32,33)(H,35,40)(H,36,39)(H,37,38)/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of human aPC				J Med Chem 49: 5047-50 (2006) Article DOI: 10.1021/jm0606950 BindingDB Entry DOI: 10.7270/Q2H994VN
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50193225 (CHEMBL424882 | {(R)-1-[6-(4-carbamimidoyl-benzylca...) Show SMILES CC(C)[C@@H](NCC(O)=O)C(=O)NC1(Cc2ccccc2-c2ccccc2C1)C(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C31H35N5O4/c1-19(2)27(34-18-26(37)38)29(39)36-31(30(40)35-17-20-11-13-21(14-12-20)28(32)33)15-22-7-3-5-9-24(22)25-10-6-4-8-23(25)16-31/h3-14,19,27,34H,15-18H2,1-2H3,(H3,32,33)(H,35,40)(H,36,39)(H,37,38)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of human thrombin activity				J Med Chem 49: 5047-50 (2006) Article DOI: 10.1021/jm0606950 BindingDB Entry DOI: 10.7270/Q2H994VN
					More data for this Ligand-Target Pair