BDBM50193244 CHEMBL378083::{1-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2-ylcarbamoyl]-cyclopentylamino}-acetic acid

SMILES: NC(=N)c1ccc(CNC(=O)C2(Cc3ccccc3C2)NC(=O)C2(CCCC2)NCC(O)=O)cc1

InChI Key: InChIKey=HCFOEEBQYUNBBT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193244   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin K-dependent protein C (Homo sapiens (Human))	BDBM50193244 (CHEMBL378083 | {1-[2-(4-carbamimidoyl-benzylcarbam...) Show SMILES NC(=N)c1ccc(CNC(=O)C2(Cc3ccccc3C2)NC(=O)C2(CCCC2)NCC(O)=O)cc1 Show InChI InChI=1S/C26H31N5O4/c27-22(28)18-9-7-17(8-10-18)15-29-23(34)26(13-19-5-1-2-6-20(19)14-26)31-24(35)25(11-3-4-12-25)30-16-21(32)33/h1-2,5-10,30H,3-4,11-16H2,(H3,27,28)(H,29,34)(H,31,35)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of human aPC				J Med Chem 49: 5047-50 (2006) Article DOI: 10.1021/jm0606950 BindingDB Entry DOI: 10.7270/Q2H994VN
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50193244 (CHEMBL378083 | {1-[2-(4-carbamimidoyl-benzylcarbam...) Show SMILES NC(=N)c1ccc(CNC(=O)C2(Cc3ccccc3C2)NC(=O)C2(CCCC2)NCC(O)=O)cc1 Show InChI InChI=1S/C26H31N5O4/c27-22(28)18-9-7-17(8-10-18)15-29-23(34)26(13-19-5-1-2-6-20(19)14-26)31-24(35)25(11-3-4-12-25)30-16-21(32)33/h1-2,5-10,30H,3-4,11-16H2,(H3,27,28)(H,29,34)(H,31,35)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of human thrombin activity				J Med Chem 49: 5047-50 (2006) Article DOI: 10.1021/jm0606950 BindingDB Entry DOI: 10.7270/Q2H994VN
					More data for this Ligand-Target Pair